Tom O’Brien is an expert on gluten sensitivity in the USA. Undigested proteins from gluten can make it into the brain and cause a range of problems. Here’s what he has to say on it’s effects
DEPRESSION
- “A study has now demonstrated that gluten is independently associated with depression in patients with NCGS.” (READ MORE)
- “Exposure to gluten specifically induced current feelings of depression.” (READ MORE)
- “Lifetime depressive symptoms may be present in one third of the CD patients who adhere to gluten free diet. Long-term adherence to the gluten-free diet may reduce the risk of current depressive symptoms.” (READ MORE)
SCHIZOPHRENIA
- Emerging scientific literature contains several reports linking gluten sensitivity states with neuropsychiatric manifestations including autism, schizophrenia, and ataxia. (READ MORE)
- Five biomarkers of gluten sensitivity were found to be significantly elevated in patients with non-affective psychoses (schizophrenia) compared to controls. (READ MORE)
AND, PERHAPS NOW IN PARKINSON’S
- Aberrant TG activity is thought to contribute to Alzheimer disease, Parkinson disease, Huntington disease, and supranuclear palsy. (READ MORE)
- a-Synuclein is a key pathogenic protein that increases in Parkinson’s disease. Elevated transglutaminase levels (the biomarker in the blood for Celiac Disease) is associated with increase a-Synuclein. (READ MORE)
- Blockade of transglutaminase activity counteracts a-synuclein accumulation in living cells. (READ MORE)